Stretch-Induced Helical Conformations in Poly(l-lysine)/Hyaluronic Acid Multilayers
نویسندگان
چکیده
منابع مشابه
Exploring polymorphisms in B-DNA helical conformations
The traditional mesoscopic paradigm represents DNA as a series of base-pair steps whose energy response to equilibrium perturbations is elastic, with harmonic oscillations (defining local stiffness) around a single equilibrium conformation. In addition, base sequence effects are often analysed as a succession of independent XpY base-pair steps (i.e. a nearest-neighbour (NN) model with only 10 u...
متن کاملHelical conformations of hexapeptides containing N-terminus diproline segments.
The role of N-terminus diproline segments in facilitating helical folding in short peptides has been investigated in a set of model hexapeptides of the type Piv-Xxx-Yyy-Aib-Leu-Aib-Phe-OMe (Piv, pivaloyl). Nine sequences have been investigated with the following N-terminus dipeptide segments: (D)Pro-Ala (4) and Pro-PsiPro (5, Psi, pseudoproline), Ala-Ala (6), Ala-Pro (7), Pro-Ala (8), Aib-Ala (...
متن کاملChiral N-substituted glycines can form stable helical conformations.
BACKGROUND Short sequence-specific heteropolymers of N-substituted glycines (peptoids) have emerged as promising tools for drug discovery. Recent work on medium-length peptoids containing chiral centers in their sidechains has demonstrated the existence of stable chiral conformations in solution. In this report, we explore the conformational properties of these N alpha chiral peptoids by molecu...
متن کاملInducing achiral aliphatic oligoureas to fold into helical conformations.
The ability of urea-linked oligomers of achiral diamines (achiral analogues of the well-established chiral oligourea foldamers) to adopt helical conformations was explored spectroscopically. Up to four achiral units were ligated either to a well-formed helical trimer or to a single chiral diamine, and the extent to which they adopted a screw-sense preference was determined by NMR and CD. In the...
متن کاملStretch-induced myosin light chain phosphorylation and stretch-release-induced tension development in arterial smooth muscle.
Stretching arteries from resting length to 1.7 times the resting length increased myosin light chain phosphorylation from 40 to 70% in a graded fashion, reaching a plateau at 1.6 times the resting length. When the fully stretched arteries were released, active tension developed without any exogenous stimulating agent. This stretch-release-induced tension approached the same magnitude as that of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: ACS Applied Materials & Interfaces
سال: 2015
ISSN: 1944-8244,1944-8252
DOI: 10.1021/acsami.5b08302